• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过卵裂球活检进行植入前基因诊断周期的妊娠结局与第3天胚胎的质量和数量均相关。

Pregnancy outcome in preimplantation genetic diagnosis cycle by blastomere biopsy is related to both quality and quantity of embryos on day 3.

作者信息

Liu Ying, Zhou Canquan, Xu Yanwen, Fang Cong, Zhang Minfang

机构信息

Reproductive Medical Center, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.

出版信息

Fertil Steril. 2009 Apr;91(4 Suppl):1355-7. doi: 10.1016/j.fertnstert.2008.03.054.

DOI:10.1016/j.fertnstert.2008.03.054
PMID:18675415
Abstract

The aim of this study was to determine the impact of day 3 embryo quality and quantity on subsequent embryonic development and pregnancy outcome following embryo biopsy. The findings demonstrate that a significantly lower proportion of poor/fair-quality embryos develop further after biopsy, and that patients with <4 good embryos on day 3 may have poor outcome. Therefore, appropriate counseling needs to be given to them before therapy is initiated.

摘要

本研究的目的是确定胚胎活检后第3天胚胎的质量和数量对后续胚胎发育及妊娠结局的影响。研究结果表明,活检后质量差/中等的胚胎进一步发育的比例显著较低,且第3天优质胚胎少于4个的患者可能预后不良。因此,在开始治疗前需要对他们进行适当的咨询。

相似文献

1
Pregnancy outcome in preimplantation genetic diagnosis cycle by blastomere biopsy is related to both quality and quantity of embryos on day 3.通过卵裂球活检进行植入前基因诊断周期的妊娠结局与第3天胚胎的质量和数量均相关。
Fertil Steril. 2009 Apr;91(4 Suppl):1355-7. doi: 10.1016/j.fertnstert.2008.03.054.
2
The combination of polar body and embryo biopsy does not affect embryo viability.极体活检与胚胎活检相结合不会影响胚胎的活力。
Hum Reprod. 2004 May;19(5):1163-9. doi: 10.1093/humrep/deh162. Epub 2004 Apr 7.
3
Pregnancies and live births after trophectoderm biopsy and preimplantation genetic testing of human blastocysts.人类囊胚滋养外胚层活检及植入前基因检测后的妊娠与活产情况。
Fertil Steril. 2005 Dec;84(6):1628-36. doi: 10.1016/j.fertnstert.2005.05.063.
4
Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of one or two blastomeres for preimplantation genetic diagnosis.用于植入前基因诊断的一或两个卵裂球活检后的诊断效率、胚胎发育及临床结局
Hum Reprod. 2008 Mar;23(3):481-92. doi: 10.1093/humrep/dem327. Epub 2007 Dec 22.
5
Comparison of development and implantation of human embryos biopsied with two different methods: aspiration and displacement.两种不同方法(抽吸法和移位法)活检的人类胚胎发育与植入情况的比较。
Fertil Steril. 2009 Aug;92(2):536-40. doi: 10.1016/j.fertnstert.2008.05.089. Epub 2008 Aug 9.
6
[First attempts in preimplantation genetic diagnosis: blastomere biopsy].植入前基因诊断的首次尝试:卵裂球活检
Orv Hetil. 2001 Nov 4;142(44):2427-30.
7
Influence of patient age on the association between euploidy and day-3 embryo morphology.患者年龄对整倍体与第 3 天胚胎形态之间关联的影响。
Fertil Steril. 2010 Jun;94(1):365-7. doi: 10.1016/j.fertnstert.2009.09.019. Epub 2009 Dec 14.
8
A simplified technique for embryo biopsy for preimplantation genetic diagnosis.一种用于植入前基因诊断的胚胎活检简化技术。
Fertil Steril. 2008 Aug;90(2):438-42. doi: 10.1016/j.fertnstert.2007.06.093. Epub 2007 Sep 19.
9
Modified laser-assisted zonal opening method for human embryo biopsy in preimplantation genetic diagnosis: preliminary experience.用于胚胎植入前基因诊断中人类胚胎活检的改良激光辅助区域打开法:初步经验
J Reprod Med. 2004 May;49(5):345-52.
10
Validation of preimplantation genetic diagnosis by PCR analysis: genotype comparison of the blastomere and corresponding embryo, implications for clinical practice.通过聚合酶链反应分析验证植入前基因诊断:卵裂球与相应胚胎的基因型比较及其对临床实践的意义
Mol Hum Reprod. 2008 Oct;14(10):573-9. doi: 10.1093/molehr/gan052. Epub 2008 Sep 18.

引用本文的文献

1
High-efficiency derivation of human embryonic stem cell lines using a culture system with minimized trophoblast cell proliferation.使用增殖性滋养层细胞最小化的培养体系高效制备人胚胎干细胞系。
Stem Cell Res Ther. 2018 May 11;9(1):138. doi: 10.1186/s13287-018-0866-5.
2
Clinical Considerations of Preimplantation Genetic Diagnosis for Monogenic Diseases.单基因疾病胚胎植入前基因诊断的临床考量
PLoS One. 2015 Sep 30;10(9):e0139613. doi: 10.1371/journal.pone.0139613. eCollection 2015.
3
The follicular microenviroment as a predictor of pregnancy: MALDI-TOF MS lipid profile in cumulus cells.
卵泡微环境作为妊娠的预测因子:MALDI-TOF MS 在卵丘细胞中的脂质谱。
J Assist Reprod Genet. 2012 Nov;29(11):1289-97. doi: 10.1007/s10815-012-9859-y. Epub 2012 Sep 12.