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患者年龄对整倍体与第 3 天胚胎形态之间关联的影响。

Influence of patient age on the association between euploidy and day-3 embryo morphology.

机构信息

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

出版信息

Fertil Steril. 2010 Jun;94(1):365-7. doi: 10.1016/j.fertnstert.2009.09.019. Epub 2009 Dec 14.

Abstract

A retrospective cohort study conducted in 138 patients undergoing their first preimplantation genetic screening (PGS) cycle between January 1, 2006, and December 31, 2007, demonstrated that embryos with good day-3 morphology were more likely to be euploid for X/Y, 8, 15, and 18 than those with poor morphology. The strength of association between euploidy and day-3 morphology was not influenced by maternal age.

摘要

一项回顾性队列研究纳入了 138 例于 2006 年 1 月 1 日至 2007 年 12 月 31 日期间进行首次胚胎植入前遗传学筛查(PGS)周期的患者,结果显示,与形态学较差的胚胎相比,形态学良好的胚胎更有可能具有 X/Y、8、15 和 18 号染色体的整倍体性。整倍体性与第 3 天形态之间的关联强度不受母体年龄的影响。

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