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患者年龄对整倍体与第 3 天胚胎形态之间关联的影响。

Influence of patient age on the association between euploidy and day-3 embryo morphology.

机构信息

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

出版信息

Fertil Steril. 2010 Jun;94(1):365-7. doi: 10.1016/j.fertnstert.2009.09.019. Epub 2009 Dec 14.

DOI:10.1016/j.fertnstert.2009.09.019
PMID:20004892
Abstract

A retrospective cohort study conducted in 138 patients undergoing their first preimplantation genetic screening (PGS) cycle between January 1, 2006, and December 31, 2007, demonstrated that embryos with good day-3 morphology were more likely to be euploid for X/Y, 8, 15, and 18 than those with poor morphology. The strength of association between euploidy and day-3 morphology was not influenced by maternal age.

摘要

一项回顾性队列研究纳入了 138 例于 2006 年 1 月 1 日至 2007 年 12 月 31 日期间进行首次胚胎植入前遗传学筛查(PGS)周期的患者,结果显示,与形态学较差的胚胎相比,形态学良好的胚胎更有可能具有 X/Y、8、15 和 18 号染色体的整倍体性。整倍体性与第 3 天形态之间的关联强度不受母体年龄的影响。

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引用本文的文献

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J Reprod Infertil. 2020 Jan-Mar;21(1):17-33.
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Feasibility of predicting live birth by combining conventional embryo evaluation with artificial intelligence applied to a blastocyst image in patients classified by age.通过将传统胚胎评估与应用于按年龄分类患者的囊胚图像的人工智能相结合来预测活产的可行性。
Reprod Med Biol. 2019 Jun 12;18(4):344-356. doi: 10.1002/rmb2.12284. eCollection 2019 Oct.
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Feasibility of artificial intelligence for predicting live birth without aneuploidy from a blastocyst image.
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Reprod Med Biol. 2019 Feb 19;18(2):204-211. doi: 10.1002/rmb2.12267. eCollection 2019 Apr.
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Feasibility of deep learning for predicting live birth from a blastocyst image in patients classified by age.深度学习用于预测不同年龄分类患者囊胚图像活产率的可行性。
Reprod Med Biol. 2019 Mar 1;18(2):190-203. doi: 10.1002/rmb2.12266. eCollection 2019 Apr.
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Erratum: Relationship between morphology, euploidy and implantation potential of cleavage and blastocyst stage embryos.勘误:卵裂期和囊胚期胚胎的形态、整倍性与着床潜能之间的关系。
J Hum Reprod Sci. 2017 Apr-Jun;10(2):142-150. doi: 10.4103/jhrs.JHRS_98_17.
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