Liu Hui-xia, Jin Pu, Zhong Zhi-an, Zhuo Sheng-qing, Tian Xiang-ting, Ou Qiong, Cen Rui-jin
Guangdong Provincial Geriatrics Institute, Guangdong Provincial People's Hospital, Guangzhou 510080, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2008 Jul;28(7):1281-3.
To understand the prevalence of sleep disordered breathing (SDB) in elderly patients with coronary artery disease (CAD) and explore the relations between SDB and CAD.
Sixty-two elderly patients with and 18 without CAD identified by coronary angiography underwent examinations by polysomnography (PSG). Left ventricular ejection fraction (LVEF) was measured by 99Tc equilibrium radionuclide angiography.
In the 62 elderly patients with CAD, 53.2% had SDB, a rate significantly higher that (22.2%) in the 18 non-CAD patients. The CAD patients with SDB had higher respiratory disturbance index (RDI) and body mass index (BMI) and lower arterial saturation of oxygen (SaO2) during sleep, with longer duration of low SPO2 (less that 90%). The incidence of hypertension was higher in CAD patients with SDB than in those without SDB. No significant correlation was found between the severity of coronary artery disease and RDI (r=-0.16, P>0.05).
The elderly patients with CAD have higher incidence of SDB, and appropriate interventions should be administered in those with severe SDB.
了解老年冠状动脉疾病（CAD）患者睡眠呼吸障碍（SDB）的患病率，并探讨SDB与CAD之间的关系。
62例经冠状动脉造影确诊的老年CAD患者和18例未患CAD的患者接受了多导睡眠图（PSG）检查。采用99Tc平衡放射性核素血管造影测量左心室射血分数（LVEF）。
62例老年CAD患者中，53.2%患有SDB，这一比例显著高于18例非CAD患者（22.2%）。患有SDB的CAD患者呼吸紊乱指数（RDI）和体重指数（BMI）较高，睡眠期间动脉血氧饱和度（SaO2）较低，低血氧饱和度（低于90%）持续时间较长。患有SDB的CAD患者高血压发病率高于未患SDB的患者。冠状动脉疾病的严重程度与RDI之间未发现显著相关性（r = -0.16，P>0.05）。
老年CAD患者SDB发病率较高，对严重SDB患者应采取适当干预措施。
