Niang Abdou, Niang Samira Elfajri, Ka El Hadji Fary, Ka Mamadou M, Diouf Boucar
Department of Nephrology, University Hospital Le Dantec, Dakar, Sénégal.
Nephrol Dial Transplant. 2008 Oct;23(10):3359-61. doi: 10.1093/ndt/gfn427. Epub 2008 Aug 1.
Authors report a 37-year-old Senegalese woman with no known history of nephropathy who was admitted for fever related to malaria, severe acute renal failure requiring dialysis with nephrotic syndrome. Biological examinations and bone marrow aspiration showed hemophagocytic syndrome. A kidney biopsy found a 'collapsing glomerulopathy' (CG). A protracted course of steroids yielded a complete, unexpected remission of the nephrotic syndrome and renal function was normal at 18 months.
作者报告了一名37岁的塞内加尔女性，她既往无肾病病史，因疟疾相关发热、伴有肾病综合征的严重急性肾衰竭需透析而入院。生物学检查和骨髓穿刺显示噬血细胞综合征。肾脏活检发现“塌陷性肾小球病”（CG）。长期使用类固醇治疗后，肾病综合征完全缓解，这一结果出乎意料，18个月时肾功能恢复正常。
