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结核相关性塌陷性肾小球病:治疗后缓解。

Tuberculosis-associated collapsing glomerulopathy: remission after treatment.

机构信息

Nephrology Division of University of São Paulo School of Medicine, São Paulo, Brazil.

出版信息

Ren Fail. 2010 Jan;32(1):143-6. doi: 10.3109/08860220903368567.

Abstract

Collapsing glomerulopathy (CG) is a severe form of nephrotic syndrome and has been mostly associated with human immunodeficiency virus (HIV) infection. Treatment response is poor, and the disease frequently leads to end-stage renal disease. More recently, CG has been described in association with other conditions, such as drug exposure and other infections, but renal prognosis remains unfavorable. This paper reports an interesting case of an HIV-negative patient with tuberculosis-related CG who needed dialysis for five months but presented full renal recovery after tuberculosis (TB) treatment and corticotherapy.

摘要

塌陷性肾小球病(CG)是肾病综合征的一种严重形式,主要与人类免疫缺陷病毒(HIV)感染有关。治疗反应不佳,疾病常导致终末期肾病。最近,CG 与其他情况有关,如药物暴露和其他感染,但肾脏预后仍然不佳。本文报道了一例有趣的 HIV 阴性结核病相关 CG 患者,该患者需要透析 5 个月,但在结核病(TB)治疗和皮质激素治疗后完全恢复了肾功能。

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