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Metabolism of T-2 toxin by rat brain homogenate.

作者信息

Yagen B, Bergmann F, Barel S, Sintov A

机构信息

Department of Natural Products, School of Pharmacy, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

出版信息

Biochem Pharmacol. 1991 Jul 25;42(4):949-51. doi: 10.1016/0006-2952(91)90058-d.

Abstract

HT-2 toxin was the sole metabolite formed when T-2 toxin was treated with homogenate from brain without its blood content. Homogenate from brain with its full blood content produced--besides HT-2 toxin--T-2 triol, neosolaniol, 4-deacetylneosolaniol and T-2 tetraol, i.e. the same metabolites formed by incubation of T-2 toxin with whole rat blood.

摘要

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