Virtanen Marianna, Pentti Jaana, Vahtera Jussi, Ferrie Jane E, Stansfeld Stephen A, Helenius Hans, Elovainio Marko, Honkonen Teija, Terho Kirsi, Oksanen Tuula, Kivimäki Mika
Finnish Institute of Occupational Health, Helsinki, Finland.
Am J Psychiatry. 2008 Nov;165(11):1482-6. doi: 10.1176/appi.ajp.2008.07121929. Epub 2008 Aug 1.
This report assessed whether hospital ward overcrowding predicts antidepressant use among hospital staff.
The extent of hospital ward overcrowding was determined using administrative records of monthly bed occupancy rates between 2000 and 2004 in 203 somatic illness wards in 16 Finnish hospitals providing specialized health care. Information on job contracts for personnel was obtained from the employers' registers. Comprehensive daily data on purchased antidepressant prescriptions (World Health Organization's Anatomical Therapeutic Chemical classification code N06A) for nurses (N=6,699) and physicians (N=641) was derived from national registers. Cox proportional hazards models were used to examine the association between bed occupancy rate and subsequent antidepressant treatment. Monthly bed occupancy rates were used as a time-dependent exposure that could change in value over the course of observation. Hazard ratios were adjusted for sex, age, occupation, type and length of employment contract, hospital district, specialty, and calendar year.
Exposure over 6 months to an average bed occupancy rate over 10% in excess of the recommended limit was associated with new antidepressant treatment. This association followed a dose-response pattern, with increasing bed occupancy associated with an increasing likelihood of antidepressant use. There was no evidence of reverse causality; antidepressant treatment among employees did not predict subsequent excess bed occupancy.
The increased risk of antidepressant use observed in this study suggests that overcrowding in hospital wards may have an adverse effect on the mental health of staff.
本报告评估医院病房过度拥挤是否可预测医院工作人员使用抗抑郁药的情况。
利用芬兰16家提供专科医疗服务的医院中203个躯体疾病病房2000年至2004年每月床位占用率的行政记录来确定医院病房过度拥挤的程度。从雇主登记册中获取人员工作合同的信息。护士(N = 6699)和医生(N = 641)购买抗抑郁药处方(世界卫生组织解剖治疗化学分类代码N06A)的综合每日数据来自国家登记册。采用Cox比例风险模型来检验床位占用率与后续抗抑郁治疗之间 的关联。每月床位占用率用作随时间变化的暴露因素,其值在观察过程中可能会改变。风险比针对性别、年龄、职业、雇佣合同类型和时长、医院辖区、专业及日历年进行了调整。
连续6个月暴露于平均床位占用率超过推荐限值10%以上与新的抗抑郁治疗相关。这种关联呈剂量反应模式,床位占用率增加与使用抗抑郁药的可能性增加相关。没有反向因果关系的证据;员工中的抗抑郁治疗并不能预测随后的床位过度占用情况。
本研究中观察到的使用抗抑郁药风险增加表明,医院病房过度拥挤可能会对工作人员的心理健康产生不利影响。