Hohenstein Katharina, Watschinger Bruno
Klinische Abteilung für Nephrologie und Dialyse, Universitätsklinik für Innere Medizin III, Medizinische Universität Wien, Wien, Austria.
Wien Med Wochenschr. 2008;158(13-14):359-64. doi: 10.1007/s10354-008-0558-3.
Hypertension and proteinuria are common risk factors for cardiovascular morbidity and mortality, as well as for the progression of renal disease. Renal functional impairment represents an independent cardiovascular risk factor by itself. Strict antihypertensive therapy and measures to maximally reduce proteinuria can substantially improve the prognosis of renal patients. This review summarizes current evidence for the role of hypertension and proteinuria with regard to renal and cardiovascular outcomes and for the importance of intensive antihypertensive and anti-proteinuric measures.
高血压和蛋白尿是心血管疾病发病和死亡以及肾脏疾病进展的常见危险因素。肾功能损害本身就是一个独立的心血管危险因素。严格的抗高血压治疗以及最大程度降低蛋白尿的措施可显著改善肾病患者的预后。本综述总结了关于高血压和蛋白尿在肾脏及心血管结局方面的作用以及强化抗高血压和抗蛋白尿措施重要性的现有证据。
