Hurt Catherine, Bhattacharyya Sarmishtha, Burns Alistair, Camus Vincent, Liperoti Rossella, Marriott Anna, Nobili Flavio, Robert Philippe, Tsolaki Magda, Vellas Bruno, Verhey Frans, Byrne Eleanor Jane
King's College London, Institute of Psychiatry, Department of Psychology, London, UK.
Dement Geriatr Cogn Disord. 2008;26(2):138-46. doi: 10.1159/000149584. Epub 2008 Aug 4.
BACKGROUND/AIMS: Behavioural and psychological symptoms have a high prevalence amongst patients with dementia and can be a significant source of distress to both patients and carers. The present study explored the relationships between quality of life and behavioural and psychological symptoms in dementia (BPSD) from both patient and carer perspectives. Contextual factors surrounding the occurrence of BPSD were explored.
Forty-six patients and 116 carers completed questionnaire measures of BPSD and quality of life.
BPSD were negatively associated with both patient and carer ratings of patient quality of life. The symptoms related to lower quality of life differed between patient and carer ratings: depression and irritability were found to predict lower carer ratings of quality of life, whilst delusions and apathy indicated lower patient ratings. Carers were found to be poor at identifying antecedents and consequences of BPSD.
The presence of BPSD is associated with lower quality of life in dementia. Interventions designed to improve the quality of life for patients should focus on the BPSD specifically associated with the patient's rating of quality of life. Information regarding the role of contextual factors in behaviour management should be made available to carers.
背景/目的：行为和心理症状在痴呆患者中普遍存在，可能给患者和照料者带来极大困扰。本研究从患者和照料者的角度探讨了痴呆患者生活质量与行为和心理症状（BPSD）之间的关系。同时探讨了BPSD发生的背景因素。
46名患者和116名照料者完成了关于BPSD和生活质量的问卷调查。
BPSD与患者及照料者对患者生活质量的评分均呈负相关。患者和照料者评分中与较低生活质量相关的症状有所不同：抑郁和易怒被发现可预测照料者对生活质量的较低评分，而妄想和冷漠则表明患者评分较低。研究发现照料者在识别BPSD的前因后果方面能力较差。
BPSD的存在与痴呆患者较低的生活质量相关。旨在提高患者生活质量的干预措施应特别关注与患者生活质量评分相关的BPSD。应向照料者提供有关背景因素在行为管理中作用的信息。
