Dolapcioglu Kenan, Gungoren Arif, Hakverdi Sibel, Hakverdi Ali Ulvi, Egilmez Ertugrul
Department of Obstetrics and Gynecology, Faculty of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey.
Arch Gynecol Obstet. 2009 Mar;279(3):431-6. doi: 10.1007/s00404-008-0737-x. Epub 2008 Aug 5.
The aim of this study was to report the clinical features, management, and outcome of two cases of complete hydatidiform mole with a coexisting viable fetus and to review the literature.
In this article, we report on the well-documented follow-up of two cases of twin pregnancies with complete hydatidiform mole and a normal fetus. Genetic amniocentesis showed normal fetal karyotype in both of two cases. In the first case, a live male infant was delivered by a cesarean section because of severe maternal bleeding at 29 weeks of gestation. In the second case, termination of pregnancy was performed due to early onset of severe preeclampsia and vaginal hemorrhage.
The chances of a live birth have been estimated between 30 and 35% and the risk of persistent trophoblastic disease is similar to singleton molar pregnancies in complete mole with coexisting fetus pregnancy. Therefore, in these pregnancies, expectant management instead of termination of pregnancy can be suggested.
本研究的目的是报告两例合并存活胎儿的完全性葡萄胎的临床特征、处理方法及结局，并复习相关文献。
在本文中，我们报告了两例双胎妊娠合并完全性葡萄胎及正常胎儿的详细随访情况。两例病例的遗传羊水穿刺均显示胎儿核型正常。第一例，因孕29周时孕妇严重出血，行剖宫产娩出一名活男婴。第二例，因早期出现严重先兆子痫和阴道出血而终止妊娠。
据估计，活产几率在30%至35%之间，持续性滋养细胞疾病的风险与合并胎儿妊娠的完全性葡萄胎单胎妊娠相似。因此，对于这些妊娠，可建议采用期待治疗而非终止妊娠。
