感染人类免疫缺陷病毒和丙型肝炎病毒的吸毒者的临床管理。

Clinical management of drug addicts infected with human immunodeficiency virus and hepatitis C virus.

作者信息

Khalsa Jag H, Vocci Frank

机构信息

Division of Pharmacotherapies and Medical Consequences of Drug Abuse, National Institute on Drug Abuse, NIH, 6001 Executive Boulevard, Bethesda, MD 20892, USA.

出版信息

J Addict Dis. 2008;27(2):1-10. doi: 10.1300/J069v27n02_01.

DOI:10.1300/J069v27n02_01

PMID:18681186

Abstract

Substance abuse and infections remain two of the major problems in the world today. Both are associated with serious morbidity and mortality, including immunological impairment leading to opportunistic infections, mental and neuropsychiatric complications of HIV and HCV infections, and liver damage of chronic HCV infection. Clinical management of substance abusers with infections is possible, available, and effective if individuals in drug treatment programs are closely monitored for adherence and compliance to HIV/HCV treatment regimens.

摘要

药物滥用和感染仍然是当今世界的两大主要问题。两者都与严重的发病率和死亡率相关，包括导致机会性感染的免疫损伤、艾滋病毒和丙型肝炎病毒感染的精神和神经精神并发症，以及慢性丙型肝炎病毒感染导致的肝损伤。如果对药物治疗项目中的个体进行密切监测，以确保其坚持并遵守艾滋病毒/丙型肝炎病毒治疗方案，那么对感染药物滥用者进行临床管理是可行的、可获得的且有效的。