Atijosan Oluwarantimi, Rischewski Dorothea, Simms Victoria, Kuper Hannah, Linganwa Bonaventure, Nuhi Assuman, Foster Allen, Lavy Chris
Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
PLoS One. 2008 Aug 6;3(7):e2851. doi: 10.1371/journal.pone.0002851.
Accurate information on the prevalence and causes of musculoskeletal impairment (MSI) is lacking in low income countries. We present a new survey methodology that is based on sound epidemiological principles and is linked to the World Health Organisation's International Classification of Functioning.
Clusters were selected with probability proportionate to size. Households were selected within clusters through compact segment sampling. 105 clusters of 80 people (all ages) were included. All participants were screened for MSI by a physiotherapist and medical assistant. Possible cases plus a random sample of 10% of non-MSI cases were examined further to ascertain diagnosis, aetiology, quality of life, and treatment needs.
6757 of 8368 enumerated individuals (80.8%) were screened. There were 352 cases, giving an overall prevalence for MSI of 5.2%. (95% CI 4.5-5.9) The prevalence of MSI increased with age and was similar in men and women. Extrapolating these estimates, there are approximately 488,000 MSI diagnoses in Rwanda. Only 8.2% of MSI cases were severe, while the majority were moderate (43.7%) or mild (46.3%). Diagnostic categories comprised 11.5% congenital, 31.3% trauma, 3.8% infection, 9.0% neurological, and 44.4% non-traumatic non infective acquired. The most common individual diagnoses were joint disease (13.3%), angular limb deformity (9.7%) and fracture mal- and non-union (7.2%). 96% of all cases required further treatment.
This survey demonstrates a large burden of MSI in Rwanda, which is mostly untreated. The survey methodology will be useful in other low income countries, to assist with planning services and monitoring trends.
低收入国家缺乏关于肌肉骨骼损伤(MSI)患病率及病因的确切信息。我们提出了一种基于合理流行病学原理且与世界卫生组织《国际功能、残疾和健康分类》相关联的新调查方法。
采用规模比例概率抽样法选取群组。通过紧凑分段抽样在群组内选取家庭。纳入了105个每组80人(各年龄段)的群组。所有参与者均由一名物理治疗师和一名医疗助理进行MSI筛查。对可能的病例以及10%非MSI病例的随机样本进行进一步检查,以确定诊断、病因、生活质量和治疗需求。
在8368名登记个体中,6757人(80.8%)接受了筛查。共发现352例病例,MSI总体患病率为5.2%。(95%可信区间4.5 - 5.9)MSI患病率随年龄增长而上升,男女患病率相似。根据这些估计进行推断,卢旺达约有48.8万例MSI诊断病例。MSI病例中只有8.2%为重度,而大多数为中度(43.7%)或轻度(46.3%)。诊断类别包括11.5%先天性、31.3%创伤性、3.8%感染性、9.0%神经性以及44.4%非创伤性非感染性后天性。最常见的个体诊断为关节疾病(13.3%)、肢体成角畸形(9.7%)以及骨折畸形愈合和不愈合(7.2%)。所有病例中有96%需要进一步治疗。
这项调查表明卢旺达MSI负担沉重,且大多未得到治疗。该调查方法将对其他低收入国家有用,有助于规划服务和监测趋势。