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Enantioselective synthesis of all-carbon quaternary stereogenic centers by catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents to five-, six-, and seven-membered-ring beta-substituted cyclic enones.

作者信息

May Tricia L, Brown M Kevin, Hoveyda Amir H

机构信息

Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA 02467, USA.

出版信息

Angew Chem Int Ed Engl. 2008;47(38):7358-62. doi: 10.1002/anie.200802910.

Abstract
摘要

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Rhodium-catalyzed enantioselective 1,2-addition of aluminum organyl compounds to cyclic enones.
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