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Enantioselective synthesis of allylsilanes bearing tertiary and quaternary Si-substituted carbons through Cu-catalyzed allylic alkylations with alkylzinc and arylzinc reagents.

作者信息

Kacprzynski Monica A, May Tricia L, Kazane Stephanie A, Hoveyda Amir H

机构信息

Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA 02467, USA.

出版信息

Angew Chem Int Ed Engl. 2007;46(24):4554-8. doi: 10.1002/anie.200700841.

DOI:10.1002/anie.200700841
PMID:17487917
Abstract
摘要

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Enantioselective synthesis of allylsilanes bearing tertiary and quaternary Si-substituted carbons through Cu-catalyzed allylic alkylations with alkylzinc and arylzinc reagents.通过铜催化的烯丙基与烷基锌和芳基锌试剂的烷基化反应对含有叔碳和季碳硅取代基的烯丙基硅烷进行对映选择性合成。
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