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Discussion Addendum for: Preparation of ()--ButylPyOx and Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids.

作者信息

Sardini Stephen R, Stoltz Brian M

机构信息

Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

出版信息

Organic Synth. 2021;98:117-130. doi: 10.15227/orgsyn.098.0117.

DOI:10.15227/orgsyn.098.0117
PMID:36247231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9558615/
Abstract
摘要

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Enabling Synthesis of ABBV-2222, A CFTR Corrector for the Treatment of Cystic Fibrosis.实现 ABBV-2222 的合成，一种用于囊性纤维化治疗的 CFTR 校正剂。
Org Lett. 2019 Jul 19;21(14):5725-5727. doi: 10.1021/acs.orglett.9b02099. Epub 2019 Jul 1.
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Total Synthesis of Caesalpinnone A and Caesalpinflavan B: Evolution of a Concise Strategy. Caesalpinnone A 和 Caesalpinflavan B 的全合成：简洁策略的演变。
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Formation of quaternary centres by copper catalysed asymmetric conjugate addition to β-substituted cyclopentenones with the aid of a quantitative structure-selectivity relationship.借助定量结构-选择性关系，通过铜催化的不对称共轭加成到β-取代环戊烯酮上形成季碳中心。
Chem Sci. 2018 Feb 5;9(9):2628-2632. doi: 10.1039/c7sc05304e. eCollection 2018 Mar 7.
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