Eukaryotic chemotaxis at a glance.
作者信息
Bagorda Anna, Parent Carole A
机构信息
Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda MD 20892-4256, USA.
出版信息
J Cell Sci. 2008 Aug 15;121(Pt 16):2621-4. doi: 10.1242/jcs.018077.
Abstract
摘要
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The regulation of cell motility and chemotaxis by phospholipid signaling.磷脂信号对细胞运动性和趋化性的调控。
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Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement.I型磷脂酰肌醇4-磷酸5-激酶控制中性粒细胞极性和定向运动。
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PDZRhoGEF and myosin II localize RhoA activity to the back of polarizing neutrophil-like cells.PDZ-Rho鸟嘌呤核苷酸交换因子和肌球蛋白II将RhoA活性定位于极化的类中性粒细胞的后部。
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Chemotaxis in Dictyostelium: how to walk straight using parallel pathways.盘基网柄菌中的趋化性：如何利用平行通路直线移动。
Curr Opin Microbiol. 2007 Dec;10(6):578-81. doi: 10.1016/j.mib.2007.10.004. Epub 2007 Nov 26.
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Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis.Iγ型磷脂酰肌醇-4-磷酸激酶是一种新型尾足成分，可调节中性粒细胞趋化过程中的尾部回缩。
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