Kuenzel W J, Blähser S
Department of Poultry Science, University of Maryland, College Park 20742.
Cell Tissue Res. 1991 Jun;264(3):481-95. doi: 10.1007/BF00319038.
Nerve fibers and perikarya containing gonadotropin-releasing hormone (GnRH-like) immunoreactivity were investigated in the brain of the three-week-old chick. Gallus domesticus using the technique of immunocytochemistry. Six major groups of perikarya were found to include the olfactory bulb, olfactory tubercle/lobus parolfactorius, nucleus accumbens, septal preoptic hypothalamic region (three sub-nuclei), lateral anterior thalamic nucleus and in and about the oculomotor complex. The immunostaining was unusual in the latter group, suggesting that the neurons may contain a GnRH-II like material. Immunoreactive fibers for GnRH were found throughout the entire brain extending from the olfactory bulbs to the caudal brainstem. Two anatomical areas, not emphasized in the past literature, which had distinct GnRH-like immunoreactivity, included the lateral anterior thalamic nucleus and the preoptic recess. The former included a group of GnRH perikarya that is also known to be a retino-recipient area while the latter contained neuronal terminals some of which appeared to be contacting the cerebrospinal fluid of the preoptic recess. An attempt was made to list all anatomical structures that contained or were juxta-positioned to sites that displayed immunoreactive perikarya and fibers including circumventricular organs.
运用免疫细胞化学技术，对三周龄家鸡（Gallus domesticus）大脑中含有促性腺激素释放激素（GnRH样）免疫反应性的神经纤维和神经核周体进行了研究。发现六组主要的神经核周体，包括嗅球、嗅结节/副嗅叶、伏隔核、隔区-视前区下丘脑区域（三个亚核）、丘脑前外侧核以及动眼神经复合体及其周围。后一组中的免疫染色情况较为特殊，提示这些神经元可能含有GnRH-II样物质。在整个大脑中均发现了GnRH免疫反应性纤维，从嗅球延伸至脑干尾部。过去文献中未着重提及的两个具有明显GnRH样免疫反应性的解剖区域，包括丘脑前外侧核和视前隐窝。前者包含一组GnRH神经核周体，该区域也是已知的视网膜接收区，而后者含有神经元终末，其中一些似乎与视前隐窝的脑脊液相接触。我们试图列出所有包含或紧邻显示免疫反应性神经核周体和纤维部位（包括室周器官）的解剖结构。
