Maberry M C, Gilstrap L C
Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, Dallas 75235-9032.
Clin Obstet Gynecol. 1991 Jun;34(2):345-51. doi: 10.1097/00003081-199106000-00016.
Acute chorioamnionitis occurs relatively frequently in pregnancy and may result in significant fetal and neonatal morbidity. Although there is no unanimity of opinion regarding the most efficacious antibiotic regimen for the treatment of this complication, there is a consensus, at least among obstetricians, that maternal treatment may have an impact on neonatal outcome. It appears that the fetus and neonate benefit from "intrauterine" treatment. Virtually all antibiotics cross the placenta, and fortunately most are relatively safe for use during pregnancy.
急性绒毛膜羊膜炎在孕期相对常见，可能导致严重的胎儿和新生儿发病。尽管对于治疗该并发症的最有效抗生素方案尚无一致意见，但至少在产科医生中存在共识，即母体治疗可能会影响新生儿结局。似乎胎儿和新生儿可从“宫内”治疗中获益。几乎所有抗生素都能穿过胎盘，幸运的是，大多数抗生素在孕期使用相对安全。
