Biesbrock Aaron R, Walters Patricia A, Bartizek Robert D, Goyal C Ram, Qaqish Jimmy G
Procter & Gamble Company, Mason, OH 45040-9462, USA.
Am J Dent. 2008 Jun;21(3):185-8.
To evaluate the plaque removal efficacy and safety of an advanced rotation-oscillation power toothbrush relative to a newly-introduced sonic toothbrush.
This study used a randomized, examiner-blind, two-treatment, four-period, four-sequence crossover design. Subjects received both toothbrushes (Oral-B Triumph and Sonicare FlexCare) and a standard dentifrice from the study site and used each toothbrush at home during an acclimation phase prior to their plaque measurement visits. After abstaining from all oral hygiene for 24 hours, subjects returned to the study site and were assessed with the Rustogi Modified Navy Plaque Index. They then brushed for 2 minutes with their first randomly-assigned toothbrush and post-brushing plaque scores were recorded. This procedure was followed for three additional study visits, with subjects using their normal at-home toothbrush and dentifrice for the 2- to 5-day washout periods between visits. Subjects always abstained from all oral hygiene for 24 hours prior to their visits.
45 subjects completed the study. Both brushes were found to be safe and both significantly reduced plaque after a single brushing. Oral-B Triumph was statistically significantly (P < 0.0001) more effective in plaque removal than Sonicare FlexCare for whole mouth plaque scores, gingival marginal plaque scores and interproximal plaque scores. Compared to Sonicare FlexCare, the adjusted mean plaque reduction scores for Oral-B Triumph were 21%, 23% and 22% greater for whole mouth, marginal and interproximal areas, respectively.
评估一款先进的旋转振荡动力牙刷相对于一款新推出的声波牙刷的牙菌斑清除效果和安全性。
本研究采用随机、检查者盲法、双治疗、四阶段、四序列交叉设计。受试者从研究地点获得两款牙刷（欧乐B Triumph和飞利浦Sonicare FlexCare）及一种标准牙膏，并在进行牙菌斑测量访视前的适应期在家中使用每款牙刷。在停止所有口腔卫生措施24小时后，受试者返回研究地点，使用Rustogi改良海军牙菌斑指数进行评估。然后他们用第一支随机分配的牙刷刷牙2分钟，并记录刷牙后的牙菌斑评分。在另外三次研究访视中重复此过程，受试者在访视之间的2至5天洗脱期使用其在家中常用的牙刷和牙膏。受试者在每次访视前始终停止所有口腔卫生措施24小时。
45名受试者完成了研究。发现两款牙刷均安全，且单次刷牙后均能显著减少牙菌斑。对于全口牙菌斑评分、牙龈边缘牙菌斑评分和邻面牙菌斑评分，欧乐B Triumph在清除牙菌斑方面在统计学上显著更有效（P < 0.0001）。与飞利浦Sonicare FlexCare相比，欧乐B Triumph在全口、边缘和邻面区域的调整后平均牙菌斑减少评分分别高出21%、23%和22%。
