Cornet A, Barbier J, Debesse B, Elhadad A, Carnot F
Sem Hop. 1976 Oct 23;52(36):1965-73.
The authors report 15 cases collected over a few years on a gastroenterology unit, and emphasize the digestive complications occurring after pelvic or abdomino-pelvic irradiation for genital carcinoma. The rectum and pelvic colon are generally affected. The delays of onset after radiotherapy may reach or exceed several months. The vascular lesions, caused by ionising radiation, explain the tissue ischemia and, consequently the failure of local medical treatment. When severe hemorrhage or visceral perforation occur, surgery is necessary. However, sutures often break down on these insufficiently vascularised tissues and re-operation is always associated with a poor prognosis.
作者报告了几年内在一个胃肠病科收集的15例病例,并强调了生殖器癌盆腔或腹盆腔放疗后出现的消化系统并发症。直肠和盆腔结肠通常会受到影响。放疗后发病延迟可能达到或超过数月。电离辐射引起的血管病变解释了组织缺血,因此局部药物治疗效果不佳。当发生严重出血或内脏穿孔时,手术是必要的。然而,在这些血管化不足的组织上缝合线往往会裂开,再次手术总是伴随着不良预后。