Cornet A, Terris G
Sem Hop. 1976 Oct 23;52(36):1981-9.
This study was carried out in 410 subjects, collecting gastric fluid for one hour, after 15 minutes emptying and one hour, after 15 minutes emptying and one hour's study of basal secretion using, as stimulant, Histalog at a maximal dose of 2 mg/kg without exceeding 130 mg. The object of this statistical analysis was to determine the average figures and the standard deviations of the volumes of secretions, together with those of the output of hydrogen ions in 5 groups of subjects: controls (60), gastric ulcers (38), duodenal ulcers (200), patients suspected of duodenal ulcer (60) or affected by dyspeptic syndrome without radiological nor endoscopic lesions (52). In the normal subject, the hydrochloric acid output was situated between 5 and 27 mEq. The diagnosis of duodenal ulcer was very unlikely when secretion was less than 9 mEq in man and almost certain above 30 mEq.
本研究对410名受试者进行，在空腹15分钟后收集胃液1小时，之后再进行1小时基础分泌研究，使用最大剂量为2mg/kg（不超过130mg）的组胺作为刺激剂。本统计分析的目的是确定5组受试者的分泌量平均值和标准差，以及氢离子输出量的平均值和标准差，这5组受试者分别为：对照组（60人）、胃溃疡患者（38人）、十二指肠溃疡患者（200人）、疑似十二指肠溃疡患者（60人）或患有消化不良综合征但无放射学及内镜病变的患者（52人）。在正常受试者中，盐酸分泌量在5至27毫当量之间。当男性分泌量低于9毫当量时，十二指肠溃疡的诊断极不可能；而当分泌量高于30毫当量时，几乎可以确诊。
