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神经囊尾蚴病:神经学、病理学、诊断及治疗方面

Neurocysticercosis: neurologic, pathogenic, diagnostic and therapeutic aspects.

作者信息

Davis L E, Kornfeld M

机构信息

Neurology Service, Department of Veterans Affairs Medical Center, Albuquerque, N. Mex.

出版信息

Eur Neurol. 1991;31(4):229-40. doi: 10.1159/000116683.

Abstract

Worldwide neurocysticercosis is the most common parasitic infection of the human brain and meninges. Clinical features of the illness vary with the stage of ova infection, but most problems arise when the mature cyst degenerates. Seizures, increased intracranial pressure, and focal neurologic signs then often develop. Computed tomography and magnetic resonance usually demonstrate Cysticercus cellulosae cysts in the brain. A new immunoblot test for antibodies to the cysticercus seems both sensitive and specific. Treatment with praziquantel or albendazole has hastened the disappearance of the cysts on computed tomography and improved clinical symptoms.

摘要

在全球范围内,神经囊尾蚴病是人类脑部和脑膜最常见的寄生虫感染。该病的临床特征因虫卵感染阶段而异,但大多数问题出现在成熟囊肿退化时。随后常出现癫痫发作、颅内压升高和局灶性神经体征。计算机断层扫描和磁共振成像通常可显示脑部的猪囊尾蚴囊肿。一种新的针对囊尾蚴抗体的免疫印迹试验似乎既敏感又特异。使用吡喹酮或阿苯达唑治疗已加速了计算机断层扫描上囊肿的消失并改善了临床症状。

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