Maxton D G, Prior A, Whorwell P J
Department of Medicine, University Hospital of South Manchester, UK.
Digestion. 1991;48(2):70-4. doi: 10.1159/000200675.
Hyperventilation is associated with some symptoms suggestive of irritable bowel syndrome and has been implicated in provoking excessive oesophageal contractility. Sixteen patients with irritable bowel syndrome were therefore studied in order to assess the effect of hyperventilation on distal colonic motility and rectal sensitivity. No significant change in either the amplitude or frequency of colonic contractile activity was noted following hyperventilation, nor was any alteration in rectal sensitivity observed. This study shows that acute hyperventilation does not affect colonic motor activity or visceral sensitivity and suggests that hyperventilation and irritable bowel syndrome are not causally related.
过度换气与一些提示肠易激综合征的症状相关，并且被认为会引发食管过度收缩。因此，对16名肠易激综合征患者进行了研究，以评估过度换气对结肠远端运动和直肠敏感性的影响。过度换气后，结肠收缩活动的幅度和频率均未出现显著变化，直肠敏感性也未观察到任何改变。这项研究表明，急性过度换气不会影响结肠运动活性或内脏敏感性，提示过度换气与肠易激综合征没有因果关系。
