用碘磷灵替代毛果芸香碱或卡巴胆碱后的眼压反应。
Intraocular pressure response to the replacement of pilocarpine or carbachol with echothiophate.
作者信息
Reichert R W, Shields M B
机构信息
Duke University Eye Center, Durham, NC 27710.
出版信息
Graefes Arch Clin Exp Ophthalmol. 1991;229(3):252-3. doi: 10.1007/BF00167878.
In 20 patients with open-angle glaucoma in aphakia or pseudophakia whose intraocular pressure had remained uncontrolled on their current medical therapy, the medication was changed from pilocarpine or carbachol to echothiophate iodide. In all, 12 patients (60%) showed a statistically significant improvement in pressure control, 7 (35%) showed no change, and 1 had higher pressure. One-third of the patients with improved intraocular-pressure control eventually required laser or incisional surgery after a mean of 23 months, whereas the remaining subjects were controlled for the duration of the follow-up, which averaged 26 months. Side effects encountered during echothiophate iodide treatment included ocular irritation, decreased vision, and one retinal detachment.
在20例无晶状体或人工晶状体眼的开角型青光眼患者中，他们当前的药物治疗未能有效控制眼压，遂将药物从毛果芸香碱或卡巴胆碱改为碘依可酯。总体而言，12例患者（60%）眼压控制有统计学意义上的显著改善，7例（35%）无变化，1例眼压升高。眼压控制得到改善的患者中有三分之一在平均23个月后最终需要激光或切开手术，而其余患者在平均26个月的随访期内眼压得到控制。碘依可酯治疗期间出现的副作用包括眼部刺激、视力下降和1例视网膜脱离。
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