Scorzin Jasmin E, Kaaden Sabine, Quesada Carlos M, Müller Christian-Andreas, Fimmers Rolf, Urbach Horst, Schramm Johannes
Department of Neurosurgery, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.
Epilepsy Res. 2008 Nov;82(1):29-37. doi: 10.1016/j.eplepsyres.2008.06.012. Epub 2008 Aug 8.
Since magnetic resonance imaging (MRI) technique is constantly evolving with higher field strength scanners, the question arises whether images from different field strength scanners can be used interchangeably for scientific and clinical purposes. We address this issue in a study group of patients with temporal lobe epilepsy (TLE). Two different quantification methods for analysing structural (MRI) were used. Conventional volumetry was performed by manually tracing amygdala and hippocampus volumes on both 1.5 and 3T scans of 10 TLE patients. Additionally a voxel-based morphometry (VBM)-based extraction of those structures was conducted. As an answer to the main question, it was determined that the volumetrically derived volumes of amygdala and hippocampus from 1.5 and 3.0T images did not differ. Our findings concerning the volumetry are consistent with findings in healthy controls, thus offering the possibility to use volumetry of the different scanners interchangeably. The results of the VBM-analyses show satisfying inter-scanner volume quantification but not consistent enough to be deemed interchangeable. Further investigations analysing the outcomes of conventional VBM of different field strength scanners are necessary.
由于磁共振成像（MRI）技术随着更高场强扫描仪的出现而不断发展，因此出现了一个问题，即来自不同场强扫描仪的图像是否可以在科学和临床应用中互换使用。我们在一组颞叶癫痫（TLE）患者中研究了这个问题。我们使用了两种不同的定量方法来分析结构（MRI）。对10例TLE患者的1.5T和3T扫描图像，通过手动描绘杏仁核和海马体的体积进行传统容积分析。此外，还基于体素形态学（VBM）对这些结构进行了提取。对于主要问题的答案是，从1.5T和3.0T图像中通过容积分析得出的杏仁核和海马体体积没有差异。我们关于容积分析的结果与健康对照组的结果一致，因此提供了在不同扫描仪之间互换使用容积分析的可能性。VBM分析结果显示扫描仪间的体积定量令人满意，但一致性不足以认为可以互换。有必要进一步研究分析不同场强扫描仪的传统VBM结果。
