Bloom Tamir, Renard Regis, Yalamanchili Praveen, Wapner Keith, Chao Wen, Lin Sheldon S
Division of Pediatric Othopaedics, Department of Orthopaedic Surgery, New Jersey Medical School-University of Medicine and Dentistry of New Jersey, 90 Bergen Street, Newark, NJ 07103, USA.
Foot Ankle Clin. 2008 Sep;13(3):363-79, viii. doi: 10.1016/j.fcl.2008.04.001.
Advances in understanding age-related changes in articular cartilage, joint homeostasis, the natural healing process after cartilage injury, and improved standards for evaluation of a joint surface made the ultimate goal of cartilage repair a possibility. New strategies for enhancement of articular cartilages' limited healing potential and biologic regeneration include advances in tissue engineering and the use of electromagnetic fields. This article reviews developments in basic science and clinical research made with these emerging technologies concerning treatment of articular cartilage defects and treatment of osteoarthritis of the ankle.
在理解关节软骨与年龄相关的变化、关节稳态、软骨损伤后的自然愈合过程以及改进关节表面评估标准方面取得的进展，使软骨修复的最终目标成为可能。增强关节软骨有限愈合潜力和生物再生的新策略包括组织工程学的进展以及电磁场的应用。本文综述了这些新兴技术在关节软骨缺损治疗和踝关节骨关节炎治疗方面基础科学和临床研究的进展。
