Sherertz E F, Jorizzo J L, White W L, Shar G G, Arrington J
Department of Dermatology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27103.
J Am Acad Dermatol. 1991 May;24(5 Pt 1):697-702. doi: 10.1016/0190-9622(91)70105-b.
Determining the best treatment for recurrent pruritic papular eruptions that do not fit well into a diagnosis (of either atopy or some other diagnosis) is sometimes frustrating. We have studied 12 patients with recurrent pruritic papular eruptions by obtaining extensive histories and by performing skin biopsies, immunofluorescence studies, and screening patch tests. The eruptions in this group are not atopic by strict criteria but have atopic features and are without a determinable exogenous cause. Histologic features resemble papular urticaria, but there is no history to suggest arthropod bites. Patients with this type of eruption have features similar to those with subacute prurigo, and they respond to variable combinations of topical or systemic corticosteroids, systemic antihistamines, and UVB or UVA. We suggest that the designation of subacute prurigo might be more appropriate for patients with these findings.
确定针对不符合(特应性或其他某种诊断)诊断标准的复发性瘙痒性丘疹性皮疹的最佳治疗方法有时令人沮丧。我们通过获取详尽病史、进行皮肤活检、免疫荧光研究及筛查斑贴试验,对12例复发性瘙痒性丘疹性皮疹患者进行了研究。该组皮疹严格按照标准不属于特应性,但具有特应性特征且无明确的外源性病因。组织学特征类似丘疹性荨麻疹,但无提示节肢动物叮咬的病史。这类皮疹患者具有与亚急性痒疹患者相似的特征,对局部或全身性皮质类固醇、全身性抗组胺药以及UVB或UVA的不同组合有反应。我们认为,对于有这些表现的患者,亚急性痒疹这一命名可能更为合适。