霉酚酸酯：正逐渐成为一种潜在的人类致畸剂。
Mycophenolate mofetil: emerging as a potential human teratogen.
作者信息
Koren Gideon
出版信息
Can Fam Physician. 2008 Aug;54(8):1112-3.
Abstract
ABSTRACTQUESTION One of my female patients conceived 2 years after renal transplant while using mycophenolate mofetil. She only realized she was pregnant at 14 weeks of gestation. How should I advise her?ANSWER Several recent case series show increased malformation rates with mycophenolate mofetil. Specifically, the repeated occurrence of phenotypic presentations of ear malformations, cleft lip and palate, and other malformations suggest that this is not by chance alone.
摘要
摘要
问题
我的一位女性患者在肾移植两年后使用霉酚酸酯期间怀孕。她直到妊娠14周才意识到自己怀孕。我该如何给她建议？
答案
最近的几个病例系列显示，使用霉酚酸酯会增加畸形率。具体而言，耳部畸形、唇腭裂及其他畸形的表型表现反复出现，这表明并非偶然。
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