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地中海人群中与代谢综合征相关的社会人口学风险因素。

Sociodemographic risk factors associated with metabolic syndrome in a Mediterranean population.

作者信息

Buckland Genevieve, Salas-Salvadó Jordi, Roure Eulàlia, Bulló Mònica, Serra-Majem Lluís

机构信息

Unit of Nutrition, Environment and Cancer, Epidemiological Research Programme, Catalan Institute of Oncology-IDIBELL, Barcelona, Spain.

出版信息

Public Health Nutr. 2008 Dec;11(12):1372-8. doi: 10.1017/S1368980008003492. Epub 2008 Aug 15.

DOI:10.1017/S1368980008003492
PMID:18702840
Abstract

OBJECTIVE

To investigate the sociodemographic risk factors associated with metabolic syndrome (MetS) in the Mediterranean population of Catalonia, Spain.

DESIGN AND SETTING

Data from the cross-sectional, population-based 2002-2003 Health Survey of Catalonia were analysed. The survey used a structured questionnaire to collect information on demographics, lifestyle and medical history. In a sub-sample of the original survey population anthropometrics and blood pressure were measured and blood samples were taken to determine HDL cholesterol, TAG and fasting glucose.

SUBJECTS

The analysis included the 1,104 individuals aged 18-74 years from this sub-sample who had complete information on all variables necessary to define MetS using the National Cholesterol Education Program's Adult Treatment Panel III (ATP III) and the International Diabetes Federation (IDF) criteria.

RESULTS

MetS prevalence was 28.5 % and 24.8 % according to IDF and ATP III criteria, respectively. MetS was significantly (P = 0.05) more common in males than females. MetS prevalence increased significantly (P<0.001) with age and degree of adiposity and as social class decreased. In general, MetS prevalence decreased as physical activity increased, which was significant (P = 0.0253) when applying ATP III criteria. After taking into account important confounders, MetS prevalence was significantly positively associated with male gender, age, BMI, physical inactivity and lower social class. Smoking status, marital status and working situation were not independently associated with MetS.

CONCLUSIONS

Age, sex, degree of adiposity, physical activity and social class are the sociodemographic risk factors independently associated with MetS in this Mediterranean population. Understanding which factors predict MetS is important considering likely increasing MetS trends, and is useful for determining public health strategies.

摘要

目的

调查西班牙加泰罗尼亚地中海人群中与代谢综合征(MetS)相关的社会人口学风险因素。

设计与背景

分析了基于人群的2002 - 2003年加泰罗尼亚横断面健康调查数据。该调查使用结构化问卷收集人口统计学、生活方式和病史信息。在原始调查人群的一个子样本中,测量了人体测量学指标和血压,并采集血样以测定高密度脂蛋白胆固醇、甘油三酯和空腹血糖。

研究对象

分析纳入了该子样本中1104名年龄在18 - 74岁的个体,这些个体具备使用美国国家胆固醇教育计划成人治疗小组第三次报告(ATP III)和国际糖尿病联盟(IDF)标准定义MetS所需的所有变量的完整信息。

结果

根据IDF和ATP III标准,MetS患病率分别为28.5%和24.8%。MetS在男性中显著(P = 0.05)比女性更常见。MetS患病率随年龄、肥胖程度增加以及社会阶层降低而显著增加(P<0.001)。总体而言,MetS患病率随体力活动增加而降低,应用ATP III标准时这一趋势显著(P = 0.0253)。在考虑重要混杂因素后,MetS患病率与男性性别、年龄、体重指数、缺乏体力活动和较低社会阶层显著正相关。吸烟状况、婚姻状况和工作情况与MetS无独立关联。

结论

年龄、性别、肥胖程度、体力活动和社会阶层是该地中海人群中与MetS独立相关的社会人口学风险因素。鉴于MetS可能的上升趋势,了解哪些因素可预测MetS很重要,且有助于确定公共卫生策略。

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