Sirdah Mahmoud M, Abu Ghali Asmaa S, Al Laham Nahed A
Biology Department, Al Azhar University-Gaza, Palestine.
Diabetes Metab Syndr. 2012 Jan-Mar;6(1):4-8. doi: 10.1016/j.dsx.2012.05.017. Epub 2012 Jun 7.
Metabolic syndrome (MetS) which is a multifaceted syndrome, has been demonstrated as a common precursor for developing cardiovascular diseases and/or type 2 diabetes mellitus. Different diagnostic definitions for MetS have been proposed and recommended. We set up to evaluate the reliabilities of the National Cholesterol Education Program's Adult Treatment Panel III (NCEP/ATP III) and the International Diabetes Federation (IDF) definitions in diagnosing MetS among Gaza Strip Palestinians.
This cross sectional study involved a randomly selected two hundred and thirty apparently healthy adults from the Gaza Strip. Anthropometric measurements, blood pressure, fasting plasma glucose, lipid profile, and questionnaire interviews were performed.
The overall prevalence of MetS in our Gaza Strip cohort was 23.0% and 39.5% according to NCEP/ATP III and IDF definitions respectively (p<0.001). No significant differences were seen in the number of MetS components in individuals having MetS by either definition (mean 3.42 ± 0.63 vs 3.52 ± 0.69 respectively, p=0.865). Both IDF and NCEP/ATP III showed an increased prevalence of MetS with age, and body mass index (BMI), however they revealed different prevalence trends with sex. Except for BMI, there were no significant differences in the general and metabolic related characteristics between subjects with MetS of IDF and NCEP/ATP III definitions.
Independently of the definition used, MetS is highly prevalent in Gaza Strip population, with a steady increase in MetS prevalence through age and BMI. The IDF definition tends to give higher values for MetS prevalence, and therefore could be more appropriate for diagnosing MetS in Gaza Strip cohort.
代谢综合征（MetS）是一种多方面的综合征，已被证明是心血管疾病和/或2型糖尿病发展的常见先兆。已提出并推荐了不同的MetS诊断定义。我们旨在评估美国国家胆固醇教育计划成人治疗专家组第三次报告（NCEP/ATP III）和国际糖尿病联盟（IDF）定义在加沙地带巴勒斯坦人中诊断MetS的可靠性。
这项横断面研究随机选取了230名来自加沙地带的表面健康的成年人。进行了人体测量、血压测量、空腹血糖检测、血脂检测和问卷调查。
根据NCEP/ATP III和IDF定义，我们加沙地带队列中MetS的总体患病率分别为23.0%和39.5%（p<0.001）。无论采用哪种定义，患有MetS的个体中MetS组分数量均无显著差异（分别为平均3.42±0.63和3.52±0.69，p=0.865）。IDF和NCEP/ATP III均显示MetS患病率随年龄和体重指数（BMI）增加，但它们显示出不同的性别患病率趋势。除BMI外，IDF和NCEP/ATP III定义的患有MetS的受试者在一般和代谢相关特征方面无显著差异。
无论使用何种定义，MetS在加沙地带人群中都非常普遍，且随着年龄和BMI的增加，MetS患病率稳步上升。IDF定义往往给出更高的MetS患病率值，因此可能更适合诊断加沙地带队列中的MetS。
