Powell A, Myles M L, Yacyshyn E
Division of Rheumatology, Department of Medicine, Alfred Hospital, Melbourne, Victoria, Australia.
Clin Rheumatol. 2008 Nov;27(11):1467-8. doi: 10.1007/s10067-008-0972-3. Epub 2008 Aug 15.
We describe a 38-year-old patient with relapsing remitting multiple sclerosis who subsequently develops systemic sclerosis following a course of interferon B-1a injections. This rare association between MS and systemic sclerosis is interesting due to the added factor of beta interferon therapy prior to the onset of the systemic sclerosis. It is also important, as more patients are treated with interferon B-1a for multiple sclerosis, this is a potential association.
我们描述了一名38岁复发缓解型多发性硬化症患者,其在接受了一段时间的干扰素β-1a注射治疗后,随后发展为系统性硬化症。多发性硬化症与系统性硬化症之间的这种罕见关联很有意思,因为在系统性硬化症发病之前存在β干扰素治疗这一附加因素。这也很重要,因为越来越多的患者使用干扰素β-1a治疗多发性硬化症,这是一种潜在的关联。