Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain.
Neurol Sci. 2011 Apr;32(2):309-11. doi: 10.1007/s10072-010-0432-0. Epub 2010 Oct 2.
We describe two multiple sclerosis patients who displayed widespread urticaria due to intramuscular interferon beta-1a (INF-β-1a). Clinicians should be aware of this adverse event, since it may be severe and it may lead to the definitive interruption of treatment. Widespread urticaria complicating intramuscular INF-β-1a therapy in multiple sclerosis should be therefore added to the list of dermatological lesions associated with interferon therapy.
我们描述了两例多发性硬化症患者，他们因肌肉内注射干扰素 β-1a（INF-β-1a）而出现广泛荨麻疹。临床医生应该意识到这种不良事件，因为它可能很严重，并可能导致治疗的最终中断。因此，多发性硬化症患者肌肉内注射 INF-β-1a 治疗中出现广泛荨麻疹应被添加到与干扰素治疗相关的皮肤病变列表中。
