Suppr超能文献

现代外科时代择期降主动脉和胸腹主动脉修复术中截瘫发生率及死亡率

Rate of paraplegia and mortality in elective descending and thoracoabdominal aortic repair in the modern surgical era.

作者信息

Misfeld M, Sievers H H, Hadlak M, Gorski A, Hanke T

机构信息

Department of Cardiac and Thoracic Vascular Surgery, University of Luebeck, Luebeck, Germany.

出版信息

Thorac Cardiovasc Surg. 2008 Sep;56(6):342-7. doi: 10.1055/s-2008-1038704.

Abstract

BACKGROUND

The risk of paraplegia and hospital death is the major concern in the surgical repair of descending and thoracoabdominal aortic pathologies. For specific indications, the evolving technology of endovascular stent grafting is becoming increasingly popular. We reviewed our results for elective surgical repair of various aortic pathologies with respect to this innovative therapeutic background.

METHODS

From July 1993 to April 2006, 56 patients (mean age 55+/-16 years, range 25 to 80 years, 62.5% males) underwent elective surgical repair of the descending (n=37, 66.1%) and thoracoabdominal aorta (n=19, 33.9%), including seven reoperations and five cases of previous endovascular stent grafting. The underlying pathologies were: degenerative aneurysm (n=21), type B aortic dissection (n=24), and Marfan's syndrome with a chronic type B dissection and an increase in the diameter of the descending aorta (n=11), respectively. Most patients were operated using deep hypothermic circulatory arrest.

RESULTS

Thirty-day mortality was 5.4 % (n=3). Two patients died of myocardial infarction, one after coronary stent occlusion. Another patient died due to ventricular disruption at the side of the left ventricular apical vent. The rate of paraplegia was 3.6% (n=2) with one case of complete and one of incomplete paraplegia. Survival at five years was 78%.

CONCLUSIONS

If modern surgical principles are used in elective descending and thoracoabdominal aortic repair, surgery can be performed with a low postoperative risk for hospital death or paraplegia. These results should be taken into account when evaluating alternative therapeutic strategies in patients with similar pathologies.

摘要

背景

截瘫风险和医院死亡风险是降主动脉及胸腹主动脉病变手术修复中的主要关注点。对于特定适应症,不断发展的血管内支架植入技术正变得越来越流行。鉴于这一创新治疗背景,我们回顾了各种主动脉病变择期手术修复的结果。

方法

1993年7月至2006年4月,56例患者(平均年龄55±16岁,范围25至80岁,62.5%为男性)接受了降主动脉(n = 37,66.1%)和胸腹主动脉(n = 19,33.9%)的择期手术修复,包括7例再次手术和5例先前接受血管内支架植入的病例。潜在病变分别为:退行性动脉瘤(n = 21)、B型主动脉夹层(n = 24)以及伴有慢性B型夹层和降主动脉直径增加的马凡综合征(n = 11)。大多数患者采用深低温循环停搏进行手术。

结果

30天死亡率为5.4%(n = 3)。2例患者死于心肌梗死,1例在冠状动脉支架闭塞后死亡。另1例患者因左心室心尖部切口处心室破裂死亡。截瘫发生率为3.6%(n = 2),1例完全性截瘫,1例不完全性截瘫。5年生存率为78%。

结论

如果在降主动脉和胸腹主动脉择期修复中采用现代手术原则,手术可在较低的术后医院死亡或截瘫风险下进行。在评估患有类似病变患者的替代治疗策略时,应考虑这些结果。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验