用于解释嘌呤类似物2-氨基-N6-羟基腺嘌呤的诱变性和特异性的碱基配对模型。
Base-pairing models to account for the mutagenicity and specificity of the purine analog 2-amino-N6-hydroxyadenine.
作者信息
Janion C
机构信息
Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw.
出版信息
Mutat Res. 1991 Aug;253(1):17-20. doi: 10.1016/0165-1161(91)90341-5.
PMID:1870607
Abstract
Potential base-pairing mechanisms of the purine analog, 2-amino-N6-hydroxyadenine (AHA), with the natural bases of DNA are presented. Base-pairing properties of this analog indicate that AHA may induce transitions and transversions of base pairs in DNA.
摘要
本文介绍了嘌呤类似物2-氨基-N6-羟基腺嘌呤（AHA）与DNA天然碱基的潜在碱基配对机制。该类似物的碱基配对特性表明，AHA可能诱导DNA中碱基对的转换和颠换。
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