Todo T, Kondo T, Shinoura N, Yamada R
Department of Neurosurgery, National Medical Center Hospital, Tokyo, Japan.
Neurosurgery. 1991 Jul;29(1):101-5; discussion 105-6.
Two cases of large, nontumorous cysts of the pineal gland are reported, the histopathology of which was confirmed using surgically resected specimens. Both patients were middle-aged, and the pineal cysts were found incidentally. The histopathological findings in the two cases were strikingly similar to each other and were characterized by the following points: 1) the cyst wall typically consisted of three layers, namely, collagenous fibers, glia-like cells, and normal pineal cells; 2) the cyst wall was relatively thin, approximately 100 to 300 microns in thickness; and 3) deposits of calcification almost always existed on the side of the layer of collagenous fiber. Because these findings are clearly different from those previously reported, large benign cysts of the pineal gland, or at least some of them, may constitute a new pathological entity. It is important to consider this possible pathological diagnosis when dealing with pineal cysts.
本文报告了两例松果体非肿瘤性大囊肿病例，并通过手术切除标本对其组织病理学进行了确认。两名患者均为中年，松果体囊肿均为偶然发现。两例病例的组织病理学表现极为相似，具有以下特点：1）囊肿壁通常由三层组成，即胶原纤维、胶质样细胞和正常松果体细胞；2）囊肿壁相对较薄，厚度约为100至300微米；3）胶原纤维层一侧几乎总有钙化沉积。由于这些发现与先前报道的明显不同，松果体大的良性囊肿，或至少其中一些，可能构成一种新的病理实体。在处理松果体囊肿时，考虑这种可能的病理诊断很重要。
