Vajtai I, Bodosi M, Varga Z, Ormos J, Vörös E
Szent-Györgyi Albert Orvostudományi Egyetem, Szeged.
Orv Hetil. 1995 Aug 27;136(35):1903-7.
Referring to two individual cases, the authors review clinical, radiological and histological features of benign glial cysts of the pineal gland. Both patients were young females with aggravating headaches and with convulsions in one case. Symptoms were referable to a space-occupying cystic mass of the pineal gland. On histology, both lesions proved to be non neoplastic cysts without an epithelial lining. Their histogenesis and low growth potential were reinforced by immunohistochemical analysis of pineal antigens and proliferation markers. Glial cysts of the pineal gland are not infrequent, but symptomatic occurrences are exceptional. Most glial cysts are of dysontogenic or degenerative origin. Sometimes, however, the role of hormonal influences or paraneoplastic factors must be considered. Symptoms caused by glial cysts of the pineal gland are non-specific and radiologic imaging technics may contribute little to etiologic diagnosis. Pineal cysts are curable by surgical resection or stereotactic decompression. Whatever the diagnostic approach, emphasis must be laid on the histologic examination in order to avoid unnecessarily aggressive treatment.
作者通过两个病例，回顾了松果体良性胶质囊肿的临床、放射学及组织学特征。两名患者均为年轻女性，其中一人伴有头痛加剧及惊厥。症状均由松果体的占位性囊性肿块引起。组织学检查显示，两个病变均为无上皮内衬的非肿瘤性囊肿。通过对松果体抗原和增殖标志物的免疫组化分析，进一步证实了其组织发生及低生长潜能。松果体胶质囊肿并不罕见，但出现症状的情况较为少见。大多数胶质囊肿起源于发育异常或退行性变。然而，有时也必须考虑激素影响或副肿瘤因素的作用。松果体胶质囊肿引起的症状无特异性，放射学成像技术对病因诊断的帮助可能不大。松果体囊肿可通过手术切除或立体定向减压治愈。无论采用何种诊断方法，都必须重视组织学检查，以避免不必要的过度治疗。
