Merle De Boever C, Mura F, Brun M, Reynes J
Service maladies infectieuses et tropicales, CHU de Montpellier, 80 avenue Augustin-Flèche, Montpellier, France.
Med Mal Infect. 2008 Sep;38(9):504-6. doi: 10.1016/j.medmal.2008.06.006. Epub 2008 Aug 15.
Bartonella henselae is the etiologic agent of the cat scratch disease and in immunocompromised patients, of bacillary angiomatosis and peliosis hepatis. Less often, ocular complications associated with B. henselae infection have been reported in immunocompetent patients and five times in HIV-infected patients. We report the case of a 42-year-old woman, coinfected by HIV-HCV, presenting with cirrhosis, who owned a cat and was hospitalized for bilateral loss of visual acuity. Ophthalmologic examination revealed bilateral papillitis with hyalitis. Nuclear magnetic resonance revealed a retrobulbar neuritis. Confirmation was given by blood tests positive for B. henselae and the exclusion of other causes of neuroretinitis with biological data. Doxycycline cured the disease rapidly.
汉赛巴尔通体是猫抓病的病原体,在免疫功能低下的患者中,也是杆菌性血管瘤病和肝紫癜的病原体。在免疫功能正常的患者中,与汉赛巴尔通体感染相关的眼部并发症较少见,在HIV感染患者中则有过5次报道。我们报告了一名42岁同时感染HIV和HCV的女性病例,该患者患有肝硬化,养了一只猫,因双眼视力丧失入院。眼科检查发现双侧乳头炎伴玻璃体炎。核磁共振显示球后视神经炎。血液检测汉赛巴尔通体呈阳性,并通过生物学数据排除了其他导致神经视网膜炎的原因,从而确诊。强力霉素迅速治愈了该疾病。