Socha Radomír, Kodrík Dalibor, Zemek Rostislav
Institute of Entomology, Biology Centre ASCR, Branisovská 31, Ceské Budejovice, Czech Republic.
Comp Biochem Physiol B Biochem Mol Biol. 2008 Nov;151(3):305-10. doi: 10.1016/j.cbpb.2008.07.014. Epub 2008 Jul 25.
In the present paper we studied the effects of five biogenic amines - norepinephrine, dopamine, octopamine, serotonin and histamine - on the locomotory activity and mobilization of lipids in the adult females of the firebug, Pyrrhocoris apterus (L.). We tested the hypothesis (1) whether the stimulation of walking activity in the bugs injected with the bioamines is associated also with their hyperlipaemic effects, like in the case of adipokinetic hormones (AKHs), and (2) whether these effects are direct or mediated through a release of the AKHs into the hemolymph. The results demonstrated that all five tested biogenic amines mobilized the fat body lipids, but only norepinephrine and dopamine were capable to enhance the walking activity simultaneously with an elevation of the lipid level in the hemolymph. Those two amines had no effect on the level of AKHs in CNS, but modulated the AKHs level in hemolymph: norepinephrine increased it, while dopamine decreased it. The results indicate an apparent feedback between AKH characteristics and dopamine and norepinephrine actions occurring in this insect species. While the stimulatory effects of norepinephrine on lipid mobilization and walking activity could involve the release of bug's own AKHs, dopamine probably employs an independent stimulatory pathway.
在本论文中，我们研究了五种生物胺——去甲肾上腺素、多巴胺、章鱼胺、5-羟色胺和组胺——对红蝽（Pyrrhocoris apterus (L.)）成年雌性的运动活性和脂质动员的影响。我们检验了以下假设：（1）注射生物胺后刺激虫子的行走活动是否也与它们的高血脂效应有关，就像促脂动激素（AKHs）的情况一样；（2）这些效应是直接的还是通过AKHs释放到血淋巴中介导的。结果表明，所有五种测试的生物胺都能动员脂肪体脂质，但只有去甲肾上腺素和多巴胺能够在提高血淋巴脂质水平的同时增强行走活动。这两种胺对中枢神经系统中AKHs的水平没有影响，但调节了血淋巴中AKHs的水平：去甲肾上腺素使其升高，而多巴胺使其降低。结果表明，在这种昆虫物种中，AKH特性与多巴胺和去甲肾上腺素的作用之间存在明显的反馈。虽然去甲肾上腺素对脂质动员和行走活动的刺激作用可能涉及虫子自身AKHs的释放，但多巴胺可能采用了一条独立的刺激途径。
