Evans A E
AJR Am J Roentgenol. 1976 Dec;127(6):891-5. doi: 10.2214/ajr.127.6.891.
Advances in pediatric oncology are reviewed using Wilms's tumor as a model. From the period when Wilms's tumor was treated by surgery alone to the time when adjuvant radiation and chemotherapy enabled attainment of an 80% survival rate, true collaboration among surgeons, radiation therapists, and pediatricians has been the key to success. The National Wilms's Tumor Study seeks to further refine treatment so that survival rates are maximized with minimum morbidity. The lessons applicable to all in cancer management are that a team approach is essential, all forms of treatment should be weighed early, treatment should be skilled and vigorous from the beginning the biology and natural history of the tumor should be considered in treatment planning, and toxicities of all forms of treatment should be respected and ways designed for their reduction.
以肾母细胞瘤为模型对儿科肿瘤学的进展进行综述。从仅通过手术治疗肾母细胞瘤的时期到辅助放疗和化疗使生存率达到80%的时期，外科医生、放疗师和儿科医生之间真正的合作一直是成功的关键。国家肾母细胞瘤研究旨在进一步优化治疗，以便在发病率最低的情况下使生存率最大化。癌症治疗中适用于所有人的经验教训是，团队方法至关重要，应尽早权衡所有治疗形式，从一开始治疗就应熟练且积极，在治疗计划中应考虑肿瘤的生物学特性和自然病程，应尊重所有治疗形式的毒性并设计降低毒性的方法。
