比利时家猫弓形虫感染率
Prevalence of Toxoplasma gondii infection in Belgian house cats.
作者信息
De Craeye Stéphane, Francart Aurelie, Chabauty Julie, De Vriendt Veerle, Van Gucht Steven, Leroux Ingrid, Jongert Erik
机构信息
Laboratory for Toxoplasmosis, Pasteur Institute of Brussels, Scientific Institute of Public Health, Brussels, Belgium.
出版信息
Vet Parasitol. 2008 Oct 20;157(1-2):128-32. doi: 10.1016/j.vetpar.2008.07.001. Epub 2008 Jul 17.
Five hundred and sixty seven sera of healthy house cats aged 3 months to 7 years, were examined for the presence of anti-toxoplasma antibodies by indirect immunofluorescence assay and compared to SAG1 and TLA enzyme linked immunosorbent assays as alternative test. Twenty-five percent of cats tested positive for IgG and/or IgM. Seroprevalence increased with age from 2% below 12 months of age up to 44% at age 7. Sensitivities of SAG1 and TLA ELISA were 84.1% and 88.6%, respectively. Peak levels in seroprevalence were correlated to increased IgG titers in TLA ELISA. Our results suggest that T. gondii infections are common in house cats and that there is a high chance for a negative cat to seroconvert in its second life-year.
对567份3个月至7岁健康家猫的血清进行检测，通过间接免疫荧光试验检测抗弓形虫抗体的存在，并与作为替代检测方法的SAG1和TLA酶联免疫吸附试验进行比较。25%的猫IgG和/或IgM检测呈阳性。血清阳性率随年龄增长而增加，12个月龄以下为2%，7岁时高达44%。SAG1和TLA酶联免疫吸附试验的敏感性分别为84.1%和88.6%。血清阳性率的峰值水平与TLA酶联免疫吸附试验中IgG滴度的增加相关。我们的结果表明，弓形虫感染在家猫中很常见，阴性猫在其第二个生命年血清转化的可能性很高。
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