Lappin M R, Greene C E, Prestwood A K, Dawe D L, Tarleton R L
Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602.
Am J Vet Res. 1989 Sep;50(9):1580-5.
Subclinical Toxoplasma gondii infection was induced in young and adult cats by oral administration of tissue cysts. An antibody-capture ELISA to detect anti-Toxoplasma IgM-class antibodies in the serum of cats was developed. The serologic response to experimental infection was followed in the 2 groups of cats by use of anti-Toxoplasma IgM and IgG detection. This study shows that anti-Toxoplasma IgM-class antibody titers develop early in the course of experimental infection in cats and that the combination of IgM- and IgG-class antibody titer measurement can aid in the detection of recent subclinical toxoplasmosis.
通过口服组织包囊，在幼年和成年猫中诱发亚临床弓形虫感染。开发了一种抗体捕获酶联免疫吸附测定法（ELISA），用于检测猫血清中的抗弓形虫IgM类抗体。通过使用抗弓形虫IgM和IgG检测，对两组猫的实验性感染血清学反应进行跟踪。本研究表明，抗弓形虫IgM类抗体滴度在猫实验性感染过程中早期出现，并且IgM类和IgG类抗体滴度测量相结合有助于检测近期的亚临床弓形虫病。
