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从与急性病毒性肝炎暴发相关的泉水中分离甲型肝炎病毒并进行序列分析。

Recovery and sequence analysis of hepatitis a virus from springwater implicated in an outbreak of acute viral hepatitis.

作者信息

Tallon Lindsay A, Love David C, Moore Zack S, Sobsey Mark D

机构信息

North Carolina Center for Public Health Preparedness, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

出版信息

Appl Environ Microbiol. 2008 Oct;74(19):6158-60. doi: 10.1128/AEM.02872-07. Epub 2008 Aug 15.

Abstract

An outbreak of acute hepatitis A virus in North Carolina was linked to drinking water from a contaminated shallow spring by phylogenetic analysis of hepatitis A virus (HAV) genomic sequences. Detection of HAV and fecal indicators in the water provided useful and timely information to assist with public health prevention and control measures.

摘要

通过对甲型肝炎病毒(HAV)基因组序列进行系统发育分析,北卡罗来纳州爆发的急性甲型肝炎疫情与受污染浅泉的饮用水有关。在水中检测到甲型肝炎病毒和粪便指示物,为协助采取公共卫生预防和控制措施提供了有用且及时的信息。

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