Capobianchi Maria R, Garbuglia Anna Rosa, Agrati Chiara, Rianda Alessia, Noto Pasquale, Corpolongo Angela, Cataldo Maria Adriana, Rosati Silvia, Zaccaro Paola, Loffredo Mariarosaria, Pompa Maria Grazia, Girardi Enrico, Scognamiglio Paola, Ippolito Giuseppe
Laboratory of Virology, National Institute for Infectious Diseases "L. Spallanzani", Via Portuense 292, 00149 Rome, Italy.
Laboratory of Virology, National Institute for Infectious Diseases "L. Spallanzani", Via Portuense 292, 00149 Rome, Italy.
Microbes Infect. 2014 Apr;16(4):362-6. doi: 10.1016/j.micinf.2014.01.003. Epub 2014 Jan 28.
Reduced circulation of hepatitis A virus lead to an increase of susceptible individuals, and outbreaks occurred recently. In Northern Italy an outbreak is ongoing, attributed to a monophyletic genotype IA strain, with mixed frozen berries as probable source. From 01/01/2013 to 07/15/2013, 30 cases were diagnosed at National Institute for Infectious Diseases, Rome, Italy, representing about twice the number of cases in whole 2012. Phylogenetic analysis indicated that most, although not all, infections were attributable to the same monophyletic genotype IA strain identified in the contemporary Northern Italy outbreak. This strain is also very similar to previous isolates from Venezuela.
甲型肝炎病毒传播减少导致易感人群增加，近期出现了疫情暴发。在意大利北部，一场疫情正在蔓延，病因是单一谱系的IA基因型毒株，冷冻混合浆果可能是传染源。2013年1月1日至2013年7月15日，意大利罗马国家传染病研究所确诊了30例病例，约为2012年全年病例数的两倍。系统发育分析表明，尽管并非所有感染病例，但大多数感染都归因于在意大利北部同时期疫情中发现的同一单一谱系IA基因型毒株。该毒株也与之前从委内瑞拉分离出的毒株非常相似。
