Huber Johannes C, Bentz Eva-Katrin, Ott Johannes, Tempfer Clemens B
University of Vienna School of Medicine, Department of Gynaecologic Endocrinology and Reproductive Medicine, Vienna, Austria.
Expert Opin Pharmacother. 2008 Sep;9(13):2317-25. doi: 10.1517/14656566.9.13.2317.
There is increasing awareness of the opportunity that many contraceptive interventions may provide for additional health benefits. However, treatment of medical problems with oral contraceptives (OCs) is often an 'off-label' practice.
The aim of this review is to summarize available data on non-contraceptive benefits of OCs.
Review of the literature.
OCs have been shown to reduce the risk of ovarian, endometrial, and colorectal cancer. It has been suggested that OCs may be used in treatment of endometriosis, menorrhagia, and uterine leiomyomas. Pelvic inflammatory disease, dysmenorrhea, premenstrual syndrome, and acne have been shown to improve under OCs.
OCs are important for global and female health. Besides contraception, non-contraceptive effects of OCs are evidence based, well established, and commonly used in clinical practice.
人们越来越意识到许多避孕干预措施可能带来额外健康益处的机会。然而，使用口服避孕药（OCs）治疗医疗问题往往是一种“非适应证”的做法。
本综述的目的是总结关于OCs非避孕益处的现有数据。
文献综述。
已证明OCs可降低卵巢癌、子宫内膜癌和结直肠癌的风险。有人提出OCs可用于治疗子宫内膜异位症、月经过多和子宫平滑肌瘤。盆腔炎、痛经、经前综合征和痤疮在使用OCs后已显示有所改善。
OCs对全球和女性健康都很重要。除了避孕作用外，OCs的非避孕效果有循证依据、已得到充分证实且在临床实践中常用。
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