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口服甾体避孕药的非避孕健康益处。

Noncontraceptive health benefits of oral steroidal contraceptives.

作者信息

Mishell D R

出版信息

Am J Obstet Gynecol. 1982 Mar 15;142(6 Pt 2):809-16. doi: 10.1016/s0002-9378(16)32492-9.

Abstract

Prospective and retrospective epidemiologic studies involving oral contraceptives have been reviewed to determine the existence and extent of their benefits other than prevention of pregnancy. There is less menstrual blood loss, which reduces the risk of iron deficiency anemia by about 50%. The incidence of menorrhagia, irregular menses, and intermenstrual bleeding is also significantly reduced in users of oral contraceptives. Studies have shown an approximate 50% reduction in risk of endometrial cancer in oral contraceptive users, as well as a significant reduction in various types of benign breast disease. Because oral contraceptives inhibit ovulation, functional ovarian cysts are nearly eliminated, and the incidence of dysmenorrhea and premenstrual tension is significantly reduced. Oral contraceptives also protect women from developing ovarian carcinoma, rheumatoid arthritis, and salpingitis. From this review we conclude that the benefits of oral contraceptives in young healthy women for far outweight their more widely publicized, infrequent risks.

摘要

为确定口服避孕药在预防妊娠之外的益处及其程度,对涉及口服避孕药的前瞻性和回顾性流行病学研究进行了综述。月经失血量减少,缺铁性贫血风险降低约50%。口服避孕药使用者的月经过多、月经不规律和经间期出血的发生率也显著降低。研究表明,口服避孕药使用者患子宫内膜癌的风险降低约50%,各种类型的良性乳腺疾病的发生率也显著降低。由于口服避孕药抑制排卵,功能性卵巢囊肿几乎消除,痛经和经前紧张的发生率显著降低。口服避孕药还能保护女性预防卵巢癌、类风湿性关节炎和输卵管炎。通过本次综述,我们得出结论:口服避孕药对年轻健康女性的益处远远超过其广为人知但不常见的风险。

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