Zhang Da, Liu Hong, Wu Xizeng
Center for Bioengineering and School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.
Phys Med Biol. 2008 Sep 21;53(18):5165-76. doi: 10.1088/0031-9155/53/18/021. Epub 2008 Aug 22.
This study presents the characterization results of a newly developed dual detector in-line phase x-ray imaging prototype. Comparison of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) for both detectors was conducted when they worked in the dual detection mode, in which two images are acquired simultaneously at a single exposure. The MTFs of the two detectors are almost identical, showing that the blurring caused by detector1 does not significantly weaken the resolving power of detector2. With a 40 kVp and 4 cm thick BR-12 phantom filtered x-ray beam, the transmittance of detector1 was measured to be 32%. The characteristic response and DQE of the two detectors almost coincide, showing that the two detectors have similar imaging performance under the imaging conditions of this study. The DQE of detector2 at the different source to detector distances (SID) also demonstrate a high level of agreement, implying that the reduced exposure level caused by elongated SID did not degrade the performance significantly. The study validated the design of the dual detection configuration for phase x-ray imaging, which has the potential for improving the accuracy of diagnostics at clinically acceptable radiation doses.
本研究展示了一种新开发的双探测器在线相位X射线成像原型的表征结果。当两个探测器在双探测模式下工作时,对它们的调制传递函数(MTF)、噪声功率谱(NPS)和探测量子效率(DQE)进行了比较,在该模式下,单次曝光可同时获取两张图像。两个探测器的MTF几乎相同,这表明探测器1引起的模糊不会显著削弱探测器2的分辨能力。使用40 kVp和4 cm厚的BR - 12体模过滤X射线束,测得探测器1的透过率为32%。两个探测器的特征响应和DQE几乎一致,这表明在本研究成像条件下,两个探测器具有相似的成像性能。探测器2在不同源到探测器距离(SID)下的DQE也显示出高度一致性,这意味着由于SID延长导致的曝光水平降低并未显著降低性能。该研究验证了用于相位X射线成像的双探测配置的设计,其有可能在临床可接受的辐射剂量下提高诊断准确性。