Mondal Santosh Kumar
Department of Pathology, Medical College, Kolkata, West Bengal, India.
Indian J Pathol Microbiol. 2008 Jul-Sep;51(3):407-8. doi: 10.4103/0377-4929.42539.
A case of primary mucosa-associated lymphoid tissue (MALT) lymphoma (marginal zone B-cell lymphoma of MALT according to WHO classification) in conjunctiva, which presented as a slowly growing salmon-colored mass at limbus of left eye is reported. Histological examination revealed a diffuse low-grade lymphoma. Immunohistochemical analysis using monoclonal antibodies showed that the tumor cells are leukocyte common antigen (CD45)+, CD20+, CD3-, CD5-, CD10- and CD43-, which confirmed the B-cell lineage of lymphoma. The case is being reported for its rarity and clinical importance of recognizing such cases because of excellent prognosis.
报告了一例原发性黏膜相关淋巴组织(MALT)淋巴瘤(根据世界卫生组织分类为MALT边缘区B细胞淋巴瘤)累及结膜,表现为左眼角膜缘处缓慢生长的鲑鱼色肿物。组织学检查显示为弥漫性低度淋巴瘤。使用单克隆抗体进行的免疫组织化学分析表明,肿瘤细胞白细胞共同抗原(CD45)阳性、CD20阳性、CD3阴性、CD5阴性、CD10阴性和CD43阴性,这证实了淋巴瘤的B细胞谱系。由于此类病例预后良好,且较为罕见,认识此类病例具有临床重要性,故予以报告。