Müller P L, Loeffler K U, Holz F G, Fischer H-P, Herwig M C
Universitäts-Augenklinik Bonn, Ernst-Abbe-Str. 2, 53127, Bonn, Deutschland.
Institut für Pathologie, Universitätsklinikum Bonn, Bonn, Deutschland.
Ophthalmologe. 2016 Jul;113(7):602-5. doi: 10.1007/s00347-015-0130-7.
An 82-year-old male patient presented with a salmon-pink colored conjunctival tumor of the left eye. A circumscribed, dense and whitish portion was detected by clinical examination. The histophological and immunhistochemical examination of the biopsy tissue revealed a CD20+ marginal zone lymphoma of the conjunctiva with amyloid deposits. Extranodal marginal zone lymphoma at this site is the most common lymphoma of the ocular adnexa and accounts for 5-10% of malignant diseases. An association with amyloid production is very rare and according to the current state of knowledge has no known impact on the outcome.
一位82岁男性患者左眼出现了鲑鱼粉红色的结膜肿瘤。临床检查发现一个边界清晰、致密且呈白色的部分。活检组织的组织学和免疫组织化学检查显示为结膜CD20 +边缘区淋巴瘤伴淀粉样沉积。该部位的结外边缘区淋巴瘤是眼附属器最常见的淋巴瘤,占恶性疾病的5 - 10%。与淀粉样物质产生相关的情况非常罕见,根据目前的知识水平,对预后尚无已知影响。