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结膜活检与眼部病变:印度东部的一项组织病理学研究。

Conjunctival biopsies and ophthalmic lesions: A histopathologic study in eastern India.

作者信息

Mondal Santosh K, Nag Dipanwita R, Bandyopadhyay Ranjana, Adhikari Anindya, Mukhopadhyay Subhalakshmi

机构信息

Department of Pathology, Medical College, Kolkata, India.

出版信息

J Res Med Sci. 2012 Dec;17(12):1176-9.

Abstract

BACKGROUND

The conjunctiva is a thin and flexible mucus membrane that provides a protective barrier to the eye. Very few histopathologic studies have been conducted on conjunctival biopsies in eastern India.

MATERIALS AND METHODS

120 conjunctival biopsies from 117 patients (76 males, 41 females) received during 8 years (January 2003-December 2010) were included in this study.

RESULTS

HISTOLOGIC DIAGNOSES WERE: degenerative lesions in 38 cases (31.66%), benign epithelial lesions in 23 cases (19.16%), premalignant and malignant epithelial lesions in 27 cases (22.5%), melanocytic lesions in 10 cases (8.33%), lymphoid in 7 cases (5.83%), and miscellaneous in 15 cases (12.5%).

CONCLUSION

Squamous papilloma was the commonest benign tumor, whereas the commonest malignant tumor was squamous cell carcinoma. Melanocytic lesions were less prevalent compared to other/western studies.

摘要

背景

结膜是一层薄而柔韧的黏膜,为眼睛提供保护屏障。在印度东部,针对结膜活检的组织病理学研究极少。

材料与方法

本研究纳入了2003年1月至2010年12月这8年间接收的117例患者(76例男性,41例女性)的120份结膜活检样本。

结果

组织学诊断结果为:退行性病变38例(31.66%),良性上皮病变23例(19.16%),癌前及恶性上皮病变27例(22.5%),黑素细胞病变10例(8.33%),淋巴样病变7例(5.83%),其他病变15例(12.5%)。

结论

鳞状乳头瘤是最常见的良性肿瘤,而最常见的恶性肿瘤是鳞状细胞癌。与其他/西方研究相比,黑素细胞病变的发生率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf3/3703171/efe082f1cf69/JRMS-17-1176-g002.jpg

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