EBV的体外转化活性。I. 由永生化的狨猴淋巴细胞产生的两种EBV毒株（M81和M72）的建立及特性
In vitro transforming activity of EBV. I-Establishment and properties of two EBV strains (M81 and M72) produced by immortalized Callithrix jacchus lymphocytes.
作者信息
Desgranges C, Lenoir G, de-Thé G, Seigneurin J M, Hilgers J, Dubouch P
出版信息
Biomedicine. 1976 Dec 5;25(9):349-52.
In vitro transformation of Callithrix jacchus marmoset lymphocytes was achieved with a nasopharyngeal carcinoma (NPC) derived Epstein-Barr virus (EBV) strain, HKLY-28. Two permanent and virus producing lymphoblastoid cell lines, M81 and M72, were obtained. Comparison between the original HKLY-28 line and both M81 and M72 lines showed that passage in the marmosets lymphocytes greatly enhanced viral production and transforming activity of the virus as observed in cottontop derived B95.8 lymphoblastoid line.
用一株源自鼻咽癌（NPC）的爱泼斯坦-巴尔病毒（EBV）毒株HKLY-28实现了狨猴淋巴细胞的体外转化。获得了两个永久性且产生病毒的淋巴母细胞系M81和M72。原始HKLY-28细胞系与M81和M72细胞系之间的比较表明，在狨猴淋巴细胞中传代极大地增强了病毒的产生以及病毒的转化活性，这在源自棉顶狨的B95.8淋巴母细胞系中也有观察到。
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